Limiteddataareavailableforclinicalcharacteristicsofpatientswithcoronavirusdisease
2019(COVID-19)outsideWuhan.Thisstudyaimedtodescribetheclinicalcharacteristicsof
COVID-19andidentifytheriskfactorsforsevereillnessofCOVID-19inJiangsuprovince,
China.ClinicaldataofhospitalizedCOVID-19patientswereretrospectivelycollectedin8
hospitalsfrom8citiesofJiangsuprovince,China.ClinicalfindingsofCOVID-19patientswere
describedandriskfactorsforsevereillnessofCOVID-19wereanalyzed.ByFeb10,2020,202
hospitalizedpatientswithCOVID-19wereenrolled.Themedianageofpatientswas44.0years
(interquartilerange,33.0-54.0).55(27.2%)patientshadcomorbidities.Attheonsetofillness,
thecommonsymptomswerefever(156[77.2%])andcough(120[59.4%]).66(32.7%)patients
hadlymphopenia.193(95.5%)patientshadabnormalradiologicalfindings.11(5.4%)patients
wereadmittedtotheintensivecareunitandnoneofthepatientsdied.23(11.4%)patientshad
severeillness.SevereillnessofCOVID-19wasindependentlyassociatedwithbodymass
index(BMI)≥28kg/m2(oddsratio[OR],9.219;95%confidenceinterval[CI],2.731to31.126;
P<0.001)andaknownhistoryoftype2diabetes(OR,4.326;95%CI,1.059to17.668;P=
0.041).InthiscaseseriesinJiangsuProvince,COVID-19patientshadlessseveresymptoms
andhadbetteroutcomesthantheinitialCOVID-19patientsinWuhan.TheBMI≥28kg/m2
andaknownhistoryoftype2diabeteswereindependentriskfactorsofsevereillnessin
patientswithCOVID-19.
Coronavirusdisease2019(COVID-19)isaninfectiousdiseasecausedbyanovelstrainof
coronavirus,severeacuterespiratorysyndromecoronavirus2(SARS-CoV-2),thatappearedin
ChinainDecember2019andspreadglobally,evolvingintothecurrentlyobservedpandemic.
•ThelaboratorydiagnosisofSARS-CoV-2infectioniscurrentlybasedonreal-timereverse
transcriptase-polymerasechainreaction(RT-PCR)testing,andimagingcannotreplace
genetictestinginpatientssuspectedofCOVID-19.However,withpredominantrespiratory
manifestationsofCOVID-19,particularlyinmoreseverecases,chestimagingusingcomputed
tomography(CT)playsamajorroleindetectingvirallunginfection,evaluatingthenatureand
extentofpulmonarylesions,andmonitoringthediseaseactivity.TheroleofchestCTasa
diagnostictoolmaybeincreasedwhenthelaboratorytestingcapacitiesusingRT-PCRprove
inaccurateorinsufficientduringamajoroutbreakofthedisease.Inthesesettings,arapid
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