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Here [otiose] means worthless or उपयोग्शून्य् and [enigma] means riddle or a paradox or पहेली.
It simply means that once the mind knows that something is impossible then it performs worthless calculations and paradoxes that even further messes up things.
On the other hand thinking in simplest way will give answer in some cases so take everything as possible and enjoy life to maximum.
Once we thinks its possible nobody can make it impossible